May I use beta-glucan simultaneously with chemo- or radiotherapy? Could it impair the effects of treatment?

Quite to the contrary. If we omit dozens of studies conducted throughout the world, pointing at the supporting effects of glucans in the treatment of cancer, glucan cetainly has a positive role in the elimination or at least suppression of negative effects due to radio- or chemotherapy. In both cases, this involves the same phenomenon - the treatment is simply targeted at a single goal - kill tumour cells. And this happens because chemotherapeutic agents or radiation kill quickly proliferating cells, i.e. mostly cancer cells. Both modes of treatment and dangerous for all types of cells and the therapy simply relies on the assumption that it is better to eliminate most cancer cells and some normal cells rather than to let malignant cells live. That is why this treatment also damages blood formation cells, which proliferate rather quickly. And this is where glucan helps, as it increases the proliferation of cells in the bone marrow, so it basically corrects what chemo- or radiotherapy damages.

Will glucan be also effective against stomach cancer? If so, what dose?

We have to realize that except for Japan, glucan is still not an officially approved medicament, even though thanks to 26 clinical trials currently underway, we are getting closer to that point. However, the Japanese authorities approved the deployment of glucan in case of gastrointestinal tumours, including stomach cancer. That is why its administration can be only recommended.

As regards the dose, the optimum dose will be about 1.5 to 2g a day, depending on the patient's tolerance. In general, doses of up to 2g would not cause any problems to adults of a regular weight, but this could be quite different in case of a disease affecting the stomach.

My father-in-law underwent a large intestine surgery (tumour). Two years later, they found two tumours in the lungs, one was surgically removed, the other was not as it is located on the vein leading to the heart. I wanted to ask you if beta-glucan could be used, which type and quantity.

Your father-in-law should definitely try beta-glucan. Cancer of the intestine and of the lungs (even in this case this rather involves secondary manifestations of the original intestinal cancer) are the two types of cancer where glucan has been tested the most. For gastrointestinal cancer, it is even approved as an official medicament in Japan, while for lung cancer clinical trials are underway. In addition, glucan can help eliminate the negative side effects of cancer treatment. Most tests are currently conducted on yeast glucan, so I can recommend this type. As regard the dose, an adult of a regular height and weight should use a dose of about 1,000mg a day.

Hello, I know that generally it is possible to use glucan against any form of cancer, but I am a bit concerned whether I can recommend it for bone marrow cancer (unfortunately I still don't know the exact type), because you write that glucan stimulates bone marrow; since I'm not an immunologist, I don't know if this could have a contradictory effect.

Bone cancer usually refers to malignant bone tumours as well as bone metastases. The difference is huge, ranging from the very type of cancer, its treatment and prognosis. In addition, we usually encounter bone tumours at a younger age, while the other group often occurs in adults. In the former case, they are tumours of hard bone parts (including cartilage), except for the very rare Ewing sarcoma. In the latter case, these are secondary metastases from a different cancer type, e.g. of the lungs or breast.

Unfortunately your question does not show which cancer type this is, but none of the types mentioned above implies that the use of beta-glucan should have any adverse reactions. It is also necessary to realize that glucan in bone marrow stimulates the growth and splitting of stem cells, which gradually become cells participating in immune reactions. Glucan is not able to stimulate the growth of all cells and has very specific effects in this regard.

Professor, I wanted to ask you about the suitability and possible dosage of beta-glucan in my case. In 1998 I was diagnosed with malignant melanoma (sign removed), which was treated with Interferonem alpha (immunotherapy) for two years, and all was well after that. Another finding in 2005 in a groin node, surgery, once again administration of interferon alpha and all well later. In 2008 metastases and chemotherapy, and also radiation. I want to believe that chemotherapy helps significantly, but also devastates the body to a large extent and it is a bit of a vicious circle. The body has to be as healthy as possible to defend itself well. I've been quite exhausted lately. I'm looking for other ways and have received information on beta-glucan, which has attracted my attention. As for medicines, I use Dacarbazin and Zometa, Rennpres, Euthyrox and Ibalgin 600. Please, what do you think about this all and if you recommend beta-glucan, what should the dose be? Thank you for your time, I appreciate it very much and I'm looking forward to your answer.

As you certainly know, malignant melanoma is one of the most aggressive forms of cancer so the very fact that you've been fighting it for 11 years clearly shows your fighting spirit. Never renounce chemotherapy, however unpleasant it may be; it is still the most essential part of any fight against cancer. Of course, it has unfavourable side effects, basically caused by the fact that the substances used in chemotherapy are essentially poisonous for all cells in our body and are only used because they kill the quickly proliferating cancer cells much faster than other, normal cells. This then results in many negative side effects, from damaged blood formation to vomiting, malaise and hair loss. Simply put: we damage our own organism in the hope of damaging cancer even more. And that is why a natural supplement will be really suitable. Beta-glucan, which is a natural preparation, is affordable and its effects have been repeatedly proven in animals as well as humans within the framework of supporting treatment of cancer as well as to eliminate the negative effects of chemotherapy and radiation. The same applies to the stimulation of the immune system, whose activity is strongly suppressed by chemotherapy. As regards the dose, the best dose will be about 1g a day, either in one or divided into several sub-doses, depending on your tolerance. Although no side effects of glucan have been described in literature, you organism may be still rather shattered after eleven years of intensive treatment. Glucan does not have any known interactions with the medicaments you've mentioned, so you shouldn't expect any problems. Good luck.

I would like to ask you if beta-glucan is suitable as a supplement in the treatment of chronic lymphatic leukemia. Thank you for your answer.

A short time ago I would have answered that we didn't know much about it, but there have been studies recently clearly demonstrating that glucan has positive effects on the treatment of this disease. There are even clinical trials underway, testing glucan for several types of leukemia. We will have to wait for their results for several years, but this does not mean that we should be waiting with the use of glucan as a supplement.

I would like to ask you if you recommend the use of beta-glucan also in support of treatment of bone metastases.

Definitely. The supporting effects of glucan have been repeatedly demonstrated on various types of cancer, therefore most recent clinical trials have dealt with the effects of glucan on cancer. Based on current results, glucan has two mechanisms of action - through direct activation of immune cells and in cooperation with antibodies, which are certainly created in case of more advanced tumours. In addition, it can be assumed that in case of metastases, treatment has already been undertaken or is currently underway, either chemotherapy or radiotherapy, and this is where the secondary effects of glucan, i.e. its ability to support blood formation, can help. At the same time it helps reduce the unpleasant side effects of the aggressive treatment of metastases. However, it has to be added that glucan only offers supporting treatment and should never replace conventional treatment prescribed by the attending physician.